Insulin resistance is a condition where the body's cells gradually become less sensitive to insulin. It leads to elevated blood sugar, increased fat storage (especially around the abdomen) and chronic low-grade inflammation. Insulin resistance is often the first step towards type 2 diabetes, heart disease, fatty liver disease — and even cancer.
Symptoms that are often overlooked
- Difficulty losing weight despite 'right' diet
- Fatigue after meals
- Constant hunger and sugar cravings
- Increasing waist circumference
- Skin changes (acanthosis nigricans)
- High blood pressure
- Elevated triglycerides and low HDL cholesterol
Up to 40% of adults in the Western world have some degree of insulin resistance — most without knowing it.
How is it diagnosed?
Standard fasting blood sugar often doesn't catch insulin resistance until it's gone too far. We measure fasting insulin, HbA1c, HOMA-IR index, triglycerides and more — to catch the problem early, when it's still fully reversible.
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Treatment strategy
- Lifestyle intervention: structured exercise (especially strength training), protein optimization, sleep hygiene
- Metabolic optimization: dietary and training adjustments based on biomarkers
- Pharmacology as needed: GLP-1 receptor agonists, SGLT2 inhibitors, metformin
- Regular follow-up with blood tests and DEXA to measure progress
Muscle mass as medical treatment
Skeletal muscle is the body's largest insulin-sensitive organ. Increased muscle mass directly improves insulin sensitivity — that's why strength training and protein optimization aren't 'lifestyle advice' but medical treatment for insulin resistance.
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